Searchable abstracts of presentations at key conferences in endocrinology

ea0025p206 | Growth and development | SFEBES2011

Effects of the prenatal environment on haematological and skeletal muscle parameters in one-week-old piglets: a role for glucocorticoids?

Fainberg Hernan , Almond Kayleigh , Bikker Paul , Symonds Michael , Mostyn Alison

Changes in maternal dietary intake during gestation can affect muscle development1 and may be linked to the catabolic actions of hormones, such as glucocorticoids, which inhibits the insulin like growth factor 1 (IGF1) pathway. This study examines the potential effects of glucocorticoids and skeletal muscle adaptations in seven-day-old offspring exposed to suboptimal gestational environments.Pregnant sows were randomly assigned to a commercial...

ea0044oc5.3 | Diabetes Mellitus and Metabolism | SFEBES2016

Depot specific transcriptional signatures of adipose tissue in sheep and humans during early life

Fainberg Hernan , Ojha Shalini , Alhaddad Ahmad , Alagal Reham , Birtwistle Mark , Davies Graeme , Castellanos Marcos , May Sean , Pelella Giussepe , Lotto Attilio , Sacks Harold , Budge Helen , Symonds Michael

The identification and characterisation of unique gene profiles expressed in specific adipose tissue depots around the body could provide novel insights on fat development.We report a comprehensive analysis of transcriptome from the five major (epicardial, pericardial, perirenal, sternal and omental) adipose depots from one week old sheep. This study also provides an integrated view of the preservation and differences between mitochondrial gene co-expres...